How safe and efficient is Zopiclone?

Comments · 141 Views

Zopiclone is a non-benzodiazepine medication used as a sedative and an anxiolytic. It is used in people with insomnia for falling asleep quickly and having an undisturbed phase of sleep, and in the treatment of daytime anxiety because of the low level of rebound insomnia associated with it

Zopiclone is available in strengths of 3.75mg and 7.5mg out of which, Zopiclone 7.5 is the most commonly used strength. It takes the drug an hour to start working on the body with peak concentrations achieved within 1.5-2 hours. The effects of Zopiclone last for 6-8 hours after which it is eliminated through the body in the form of metabolic wastes

How efficient and safe is Zopiclone for insomnia and anxiety

Zopiclone dosages of 7.5mg have demonstrated efficacy equivalent to Flurazepam 30mg/day and Nitrazepam 5mg/day, two potent medications used in the short-term treatment of sleep insufficiency. In addition to the above-mentioned drugs, the use of Zopiclone 7.5 has been proven to have similar efficacy to that of flunitrazepam 1 to 2 mg, temazepam 20 mg, triazolam 0.125 to 0.5 mg and midazolam 15 mg used daily: Flunitrazepam is used in severe insomnia conditions and to assist with anesthesia, Temazepam is used to treat severe or debilitating insomnia, Triazolam, being a central nervous system (CNS) depressant tranquilizer, and Midazolam for anesthesia and procedural sedation. All of these medications belong to the benzodiazepine group and have potent anxiolytic qualities. zopiclone has an equivalent efficacy profile but an improved safety profile as a short-term treatment for insomnia conditions.

Buy Zopiclone Online-treated patients reported themselves to be less impaired by daytime sedation than patients treated with flurazepam, nitrazepam, and flunitrazepam. The further comparison proved that Zopiclone and temazepam showed similar effects on daytime behavior while zopiclone worked better on daytime well-being than triazolam and midazolam.

Data from clinical trials, pooled analyses, and postmarketing surveillance including over 30,000 patients have shown that bitter taste is one of the chief side-effects associated with the use of the medication and apart from the bitter taste that was observed by more than 10% of subjects receiving Zopiclone, the tolerability was similar to that of placebo. The medication is safe to use when used within limits.

Clinical trials found no evidence for significant rebound insomnia during the evaluation of the drug and indicated that the risk of withdrawal reactions with therapeutic doses of zopiclone is very low. In addition, Zopiclone has a lower dependence potential as well if used on a short-term basis and discontinued after the time limit. But addiction potential is apparent in patients with a history of addiction and psychiatric illness and in such conditions, use of the medication can lead to considerable damage greater in intensity than therapeutic benefits.

Evaluation of the accumulated evidence from over 2.5 billion units dispensed in more than 30 countries indicates that zopiclone is effective, well tolerated, and an excellent alternative to benzodiazepines in the short-term treatment of insomnia as long as used judiciously for a short-term basis.

Before you buy, be aware of the potential side effects of zopiclone. Some common side effects include drowsiness, dizziness, and headache. If you experience any of these side effects, speak to a healthcare professional right away.

It is also important to follow the directions on the label when taking zopiclone. Do not take more or less than directed, and do not stop taking the medication without speaking to your doctor first. Taking too much zopiclone can be dangerous, so it is important to follow the directions carefully.

Read more
Comments